ORAI2 antibody detects human ORAI. Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3. Anti-ORAI2 antibodies are ideal for investigators involved cell cycle protein and enzyme research.
Anti-ORAI2 Antibody is suitable for use in E,WB, and ICC. Expect a band approximately ~28.5 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Type: Primary
Antigen: ORAI2
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: