Anti-NBN Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

600-401-DB0

75930-428EA 635.22 USD

75930-428

Anti-NBN Rabbit Polyclonal Antibody

Antibodies

NIBRIN (NBN) is a member of the double-strand break repair complex MRE11/RAD50/NBN (MRN) which is involved in DNA double-strand break repair, DNA damage-induced checkpoint activation and plays a critical role in the maintenance of chromosome integrity. NIBRIN contains two modules found in cell cycle checkpoint proteins, a forkhead-associated domain adjacent to a breast cancer carboxy-terminal domain. Mutations in this gene are associated with Nijmegen breakage syndrome and maybe the cause of cancer predisposition and aplastic anemia.

Anti-NIBRIN Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 85 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: NBN
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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