Anti-MFN2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

MFN2 antibody 100 µg

MFN2 antibody 100 µg

600-401-CT9

75929-928EA 635.22 USD

75929-928

Anti-MFN2 Rabbit Polyclonal Antibody

Antibodies

Mitofusin 2 (MFN2) and the related protein MFN1 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN2 is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. MFN2 has two key domains: a coiled coil region that mediates MFN2 binding and a GTPase domain that likely plays a role in fusion (3,4). Both domains are essential for embryonic development and may play a role in the pathobiology of obesity. Overexpression of MFN2 causes mitochondrial dysfunction and cell death (5).

Anti-MFN2 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 86 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: MFN2
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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