Anti-LZTS2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Anti-LZTS2 Rabbit polyclonal antibody

Anti-LZTS2 Rabbit polyclonal antibody

600-401-CP4

75929-768EA 635.22 USD

75929-768

Anti-LZTS2 Rabbit Polyclonal Antibody

Antibodies

The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.

Anti-LZTS2 Antibody has been tested for use in ELISA, and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 73 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: LZTS2
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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