Human Recombinant IL-17AF Heterodimer

Supplier: Rockland Immunochemical

009-001-V56-0100 009-001-V56-0025 009-001-V56-0005

75928-790EA 8502 USD

75928-790 75929-076 75929-082 75929-088

Human Recombinant IL-17AF Heterodimer

Proteins and Peptides

Recombinant Human IL-17AF Heterodimer control protein

Control Protein
PCA Assays
ImmunoBlot

Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17RA receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant human IL-17AF is a non-glycosylated heterodimer, containing one IL-17A subunit and one IL-17F subunit. The dimer has a total of 271 amino acids, with an approximate molecular weight of 30.7 kDa.

Interleukin-17AF Heterodimer Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Interleukin-17AF Heterodimer in immunological assays.

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