QuantiChrom™ Mannosidase Assay Kit, BioAssay Systems

Supplier: BIOASSAY SYSTEMS

QuantiChrom™ Mannosidase Assay Kit, BioAssay Systems

QuantiChrom™ Mannosidase Assay Kit, BioAssay Systems

DAMA-100

75877-956EA 614.72 USD

75877-956

QuantiChrom™ Mannosidase Assay Kit, BioAssay Systems

Assays Enzyme Assays

For quantitative determination of alpha-mannosidase enzyme activity.

Linear detection range 1 to 250 U/L for a 10-minute reaction
This homogeneous "mix-incubate-measure" type assay can be readily automated for processing thousands of samples per day

α-Mannosidase (AMA) is an enzyme which catalyzes the cleavage of the α form of mannose. α-Mannosidase assists in the breakdown of complex sugars from glycoproteins in the lysosome. Defective AMA or deficient AMA activity causes α-mannosidosis and leads to deterioration of the central nervous system in children. BioAssay Systems’ non-radioactive, colorimetric AMA assay is based on the cleavage of 4-nitrophenol from the synthetic substrate. Nitrophenol becomes intensely colored after addition of the stop reagent. The increase in absorbance at 405 nm after addition of the stop reagent is directly proportional to the enzyme activity.

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