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Anti-CD28 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: CD28.2]

Supplier: BIOGEMS INTERNATIONAL INC.

10311-77-100

75844-286EA 322.61 USD

75844-286

Anti-CD28 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: CD28.2]

Antibodies

The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.

Type: Primary
Antigen: CD28
Clonality: Monoclonal
Clone: CD28.2
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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