Anti-CD45.2 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 104]

Supplier: BIOGEMS INTERNATIONAL INC.
07532-77-25
75844-182EA 70.97 USD
75844-182
Anti-CD45.2 Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 104]
Antibodies
The 104 monoclonal antibody specifically reacts with the MouseCD45 molecule, the Leukocyte Common Antigen (LCA) which occurs in the alloantigen CD45.2-expressing Mousestrains (C57BL/6, CBA, 129, A, AKR, C58, DBA/1, DBA/2, BALB/c, and C3H/He). The 104 monoclonal antibody does not react with the leukocytes of the CD45.1-expressing Mousestrains (DA, SJL/J, RIII, and STS/A). The CD45 molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region’s variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the Mousestrains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction. The 104 antibody inhibits some of the B lymphocytes responses, reduces the serum IgG levels, and influences the autoimmune renal pathology.

Type: Primary
Antigen: CD45.2
Clonality: Monoclonal
Clone: 104
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Mouse
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