Anti-CD3e Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: 145-2C11]

Supplier: BIOGEMS INTERNATIONAL INC.
05122-80-25
75843-838EA 70.97 USD
75843-838
Anti-CD3e Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: 145-2C11]
Antibodies
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa ε chain of the TCR complex. Together with the γ and δ subunits of CD3, the ε subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the ε chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.

Type: Primary
Antigen: CD3e
Clonality: Monoclonal
Clone: 145-2C11
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR