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Anti-CD3e Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 145-2C11]

Supplier: Biogems

05122-77-100

75843-832EA 206.45 USD

75843-832

Anti-CD3e Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: 145-2C11]

Antibodies

The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa Îµ chain of the TCR complex. Together with the Î³ and Î´ subunits of CD3, the Îµ subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the Îµ chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.

Type: Primary
Antigen: CD3e
Clonality: Monoclonal
Clone: 145-2C11
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse

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