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Anti-CD44 Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: IM7]

Supplier: BIOGEMS INTERNATIONAL INC.

06511-77-25

75842-946EA 96.79 USD

75842-946

Anti-CD44 Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: IM7]

Antibodies

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Human

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