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Anti-IL-17A Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 17B7]

Supplier: BIOGEMS INTERNATIONAL INC.

73812-50-50

75842-498EA 338.58 USD

75842-498

Anti-IL-17A Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 17B7]

Antibodies

The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.

Type: Primary
Antigen: IL-17A
Clonality: Monoclonal
Clone: 17B7
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rat
Isotype: IgG2a, kappa
Reactivity: Mouse

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