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Anti-CD44 Rat Monoclonal Antibody (BG Violet 450) [clone: IM7]

Supplier: BIOGEMS INTERNATIONAL INC.

06511-40-25

75841-830EA 109.51 USD

75841-830

Anti-CD44 Rat Monoclonal Antibody (BG Violet 450) [clone: IM7]

Antibodies

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: IM7
Conjugation: BG Violet 450
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Human

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