Anti-IFIH1 Mouse Monoclonal Antibody [clone: Hely-1]

Supplier: Prosci
36-114
75793-032EA 727.15 USD
75793-032
Anti-IFIH1 Mouse Monoclonal Antibody [clone: Hely-1]
Antibodies
RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

Immunoprecipitation: (1:100). Western Blot: (1:1‘000).

Type: Primary
Antigen: IFIH1
Clonality: Monoclonal
Clone: Hely-1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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