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Anti-GATA3 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Anti-beta Amyloid pyro E3 Immunofluorescence

Anti-GATA3 Rabbit polyclonal antibody

Immunohistochemistry of GATA3 Antibody

Anti-beta Amyloid pyro E3 Immunofluorescence

Anti-GATA3 Rabbit polyclonal antibody

Immunohistochemistry of GATA3 Antibody

600-401-BJ7

10802-958EA 635.22 USD

10802-958

Anti-GATA3 Rabbit Polyclonal Antibody

Antibodies

GATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunohistochemsitry: 2.5 ?g/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1-2 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: GATA3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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