Anti-FAM129B Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

600-401-X06

10802-744EA 656.12 USD

10802-744

Anti-FAM129B Rabbit Polyclonal Antibody

Antibodies

FAM129B, also known as Niban-like protein 1, belongs to a poorly characterized protein family with unknown category and function. Increased expression of the Niban gene has been observed in renal carcinomas. Suppression of FAM129B expression in HeLa cells has been seen to promote apoptosis, suggesting that it can modulate cell death signaling, and may be involved in the ER stress response. FAM129B is also up-regulated in various types of thyroid tumors and Hashimoto’s thyroiditis. It has been suggested that the MAP kinase dependent phosphorylation of FAM129B is important in controlling melanoma cells, as inhibition of B/Raf/MKK/ERK in melanoma cells represses invasion. It is believed that phosphorylated FAM129B not only derepresses invasion, but also regulates events that promote invasion. FAM129B pS679/683 Antibody is ideal for researchers interested in cancer research.

Recommended Dilutions: ELISA: 1:10,000; Western Blot: 1:1000;

Type: Primary
Antigen: FAM129B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Internal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Non-Human Primate

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