Anti-BAG1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Immunofluorescence of BAP29 Antibody

Anti-BAG1 Rabbit Polyclonal Antibody

Western Blot of BAG-1 Antibody

Immunofluorescence of BAG-1 Antibody

Western Blot of BAP29 Antibody

Immunofluorescence of BAP29 Antibody

Anti-BAG1 Rabbit Polyclonal Antibody

Western Blot of BAG-1 Antibody

Immunofluorescence of BAG-1 Antibody

Western Blot of BAP29 Antibody

600-401-Z22

10801-982EA 635.22 USD

10801-982

Anti-BAG1 Rabbit Polyclonal Antibody

Antibodies

Bcl-2-associated athanogene 1 (BAG-1) was first identified as an anti-apoptotic bcl-2-binding protein. Later it was found to bind the molecular chaperones Hsp70 and Hsc70 through its carboxy-terminal sequence (termed the Bag domain), resulting in the inhibition of the refolding activity of these chaperones. It is thought that by binding and inhibiting these molecular chaperones, BAG-1is able to modulate the expression level of proteins requiring chaperones to fold correctly. One such group of proteins that are affected is glucocorticoid receptors. Other reports have suggested that the level of BAG-1 expression correlates with the aggressiveness of various cancers. Multiple isoforms of BAG-1 are known to exist.

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunohistochemsitry: 2 µg/mL; Immunofluorescence Microscopy: 20 µg/mL; Western Blot: 1 - 2 µg/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: BAG1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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