Anti-ATXN1 Mouse Monoclonal Antibody (Biotin) [clone: S76-8]

Supplier: Rockland Immunochemical

200-306-W69

10801-946EA 582.99 USD

10801-946

Anti-ATXN1 Mouse Monoclonal Antibody (Biotin) [clone: S76-8]

Antibodies

Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons.

Recommended Dilutions: ELISA: 1:10,000; Immunohistochemsitry: User Optimized; Immunoprecipitation: User Optimized; Western Blot: 1:1000; 0.1% (w/v) Sodium Azide

Type: Primary
Antigen: ATXN1
Clonality: Monoclonal
Clone: S76-8
Conjugation: Biotin
Epitope: Center
Host: Mouse
Isotype:
Reactivity: Human, Rat, Mouse

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