Anti-GFAP Mouse Monoclonal Antibody (Biotin) [clone: S206B-9]

Supplier: Rockland Immunochemical

200-306-W56

10801-628EA 582.99 USD

10801-628

Anti-GFAP Mouse Monoclonal Antibody (Biotin) [clone: S206B-9]

Antibodies

The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. Anti-GFAP is ideal for investigators involved in Neuroscience Research, including Alexander Disease, Oligodendroglioma, Cytoskleton Remolding Neurofilaments and PIP3/AKT Signaling.

Recommended Dilutions: ELISA: 1:10,000; Immunohistochemsitry: User Optimized; Western Blot: 1:1000; 0.1% (w/v) Sodium Azide

Type: Primary
Antigen: GFAP
Clonality: Monoclonal
Clone: S206B-9
Conjugation: Biotin
Epitope: C-terminal
Host: Mouse
Isotype:
Reactivity: Human, Rat, Mouse

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