Anti-GABARAPL2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Anti-GABARAPL2 Rabbit polyclonal antibody

Anti-GABARAPL2 Rabbit polyclonal antibody

600-401-BJ1

10801-522EA 635.22 USD

10801-522

Anti-GABARAPL2 Rabbit Polyclonal Antibody

Antibodies

Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system (1). It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2). GABARAPL2 (GABAA receptor-associated protein-like 2), also known as GATE16, was initially identified as a membrane transport modulator and is a mammalian ortholog to the autophagy protein ATG8 (3,4). It is thought that GABARAPL2 and other members of the ATG8 family act as scaffolds for assembly of the Unc-51 like kinase (ULK) complex in the formation of autophagosomes (5).

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunohistochemsitry: 5 ?g/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1-2 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: GABARAPL2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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