Anti-CXCR4 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

600-401-G93

10801-100EA 635.22 USD

10801-100

Anti-CXCR4 Rabbit Polyclonal Antibody

Antibodies

DcR2 antibody detects human DcR2 precursor. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis. Anti-DcR2 antibodies are ideal for investigators involved in NFkappaB, Apoptosis, Cytokine and Growth factor research.

Recommended Dilutions: Western Blot: 1:2000; contains 0.01% (w/v) Sodium Azide

Type: Primary
Antigen: CXCR4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Center
Host: Rabbit
Isotype:
Reactivity:

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