Anti-PTGDR2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Western Blot of CTRP1 Antibody

Anti-PTGDR2 Rabbit Polyclonal Antibody

Western Blot of CRTH2 Antibody

Immunofluorescence of CRTH2 Antibody

Western Blot of CTRP1 Antibody

Anti-PTGDR2 Rabbit Polyclonal Antibody

Western Blot of CRTH2 Antibody

Immunofluorescence of CRTH2 Antibody

600-401-AP0

10800-924EA 635.22 USD

10800-924

Anti-PTGDR2 Rabbit Polyclonal Antibody

Antibodies

The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor. CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo. At least two different isoforms of CRTH2 are known to exist.

Recommended Dilutions: ELISA: 1:10,000; Immunohistochemsitry: 2.5 µg/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: PTGDR2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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