Anti-CRIM1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

600-401-AN3

10800-906EA 635.22 USD

10800-906

Anti-CRIM1 Rabbit Polyclonal Antibody

Antibodies

CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

Recommended Dilutions: ELISA: 1:10,000; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CRIM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity:

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