Anti-CD33 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical
600-401-AG8
10800-672EA 635.22 USD
10800-672
Anti-CD33 Rabbit Polyclonal Antibody
Antibodies
CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Western Blot: 1-2 ?g/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CD33
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope: Center
Host: Rabbit
Isotype:
Reactivity:
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