Anti-ATG4D Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Anti-ATG4D Rabbit Polyclonal Antibody

Anti-ATG4D Rabbit Polyclonal Antibody

600-401-Y85

10800-214EA 635.22 USD

10800-214

Anti-ATG4D Rabbit Polyclonal Antibody

Antibodies

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4D, also known as AUTL4, is one of four mammalian orthologs of the yeast ATG4 protein; all four are cysteine proteases (3). ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes. In mammals, each ATG4 homolog shows a selective preference for the ATG8 homologs (4).

Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunohistochemsitry: 2.5 ?g/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 1 - 2 µg/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: ATG4D
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat

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