Anti-AP2M1 Chicken Polyclonal Antibody

Supplier: Rockland Immunochemical

600-901-G75

10800-040EA 635.22 USD

10800-040

Anti-AP2M1 Chicken Polyclonal Antibody

Antibodies

AP2M1 antibody detects human AP2M1. The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist. Anti-AP2M1 antibodies are ideal for investigators involved in infectious disease and enzyme research.

Recommended Dilutions: Western Blot: 1-2 ug/mL; contains 0.01% (w/v) Sodium Azide

Type: Primary
Antigen: AP2M1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Chicken
Isotype:
Reactivity: Human, Mouse, Rat

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