Anti-CD5L Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical
600-401-X88
10799-616EA 635.22 USD
10799-616
Anti-CD5L Rabbit Polyclonal Antibody
Antibodies
Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.

Recommended Dilutions: ELISA: 1:5000-1:20,000; Immunohistochemsitry: 10 ?g/mL; Western Blot: 0.5 - 2 µg/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: CD5L
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity:
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