Anti-FYB Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Western Blot of AES Antibody

ADAP N-TERM antibody 100 µg

Western Blot of ADAP Antibody

Immunofluorescence of ADAP Antibody

Western Blot of AES Antibody

ADAP N-TERM antibody 100 µg

Western Blot of ADAP Antibody

Immunofluorescence of ADAP Antibody

600-401-X71

10799-578EA 635.22 USD

10799-578

Anti-FYB Rabbit Polyclonal Antibody

Antibodies

The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kB family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.

Recommended Dilutions: ELISA: 1:5000-1:10000; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 0.5-1 µg/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: FYB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-terminal
Host: Rabbit
Isotype:
Reactivity: Human

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