Anti-ACE2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Immunocytochemistry of Acinus Antibody

Human ACE2 antibody 100 µg

Immunohistochemistry of ACE2 Antibody

Western Blot of Acinus Antibody

Immunofluorescence of ACE2 Antibody

Immunocytochemistry of Acinus Antibody

Human ACE2 antibody 100 µg

Immunohistochemistry of ACE2 Antibody

Western Blot of Acinus Antibody

Immunofluorescence of ACE2 Antibody

600-401-X60

10799-534EA 635.22 USD

10799-534

Anti-ACE2 Rabbit Polyclonal Antibody

Antibodies

Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.

Recommended Dilutions: ELISA: 1:5000-1:20,000; Immunohistochemsitry: 2 µg/mL; Immunofluorescence Microscopy: 20 ?g/mL; Western Blot: 0.5 - 2 µg/mL; contains 0.02% (w/v) Sodium Azide

Type: Primary
Antigen: ACE2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Center
Host: Rabbit
Isotype:
Reactivity: Human

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