Anti-NP Rabbit Polyclonal Antibody

Supplier: Prosci

ELISA results using Seasonal H1N1 Nucleocapsid Protein antibody at 1 µg/ml and the blocking and corresponding peptides at 60, 10, 2 and 0 ng/ml.

ELISA results using Seasonal H1N1 Nucleocapsid Protein antibody at 1 µg/ml and the blocking and corresponding peptides at 60, 10, 2 and 0 ng/ml.

5361_S

10749-146EA 191.02 USD

10749-146

Anti-NP Rabbit Polyclonal Antibody

Antibodies

Seasonal H1N1 Nucleocapsid Protein Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP), thought to control whether mRNA or cRNA is produced. The nucleoprotein (NP), which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses. It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently. This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.

Type: Primary
Antigen: NP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Virus

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