Anti-LCMV Protein Z Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss

BS-6946R-CY5

10458-414EA 803.92 USD

10458-414

Anti-LCMV Protein Z Rabbit Polyclonal Antibody (Cy5®)

Antibodies

Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L (By similarity). Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. Also selectively represses protein production by associating with host eIF4E

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: LCMV Protein Z
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Virus

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