Bevacizumab (mAb-based) ELISA Assay Kit, Eagle Biosciences, Inc.
Supplier: Eagle Biosciences
Bevacizumab mAb-based ELISA precisely measures free Bevacizumab in serum and plasma samples.
- Dynamic Range: 6 - 200 ng/mL
- Sensitivity: 2 ng/mL
- Incubation: 2 hours
The drug Bevacizumab (trade name Avastin® ) is a recombinant human IgG1::k monoclonal antibody specific for all human vascular endothelial growth factor-A (VEGF-A) isoforms and it has been approved by the FDA as a first-line treatment for metastatic colorectal cancer in combination with chemotherapy. Furthermore, VEGF is implicated in intraocular neovascularization associated with diabetic retinopathy and age-related macular degeneration. The specificity of this testsystem is achieved by using a monoclonal antibody named "MAY-2B5" for the coating of the microtiter plate. This antibody is specific for Bevacizumab only and does not cross react with other VEGF catchers.
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