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MMP-7 ELISA, Eagle Biosciences

Supplier: Eagle Biosciences

MM731-K01

102994-792EA 1405.77 USD

102994-792

MMP-7 ELISA, Eagle Biosciences

Assays ELISAs

MMP-7 ELISA is intended to detect the Cancer Antigen MMP-7 concentration in human serum.

Dynamic Range: 1 - 256 ng/ml
Sensitivity: 1 ng/ml
Incubation: 3 hours

MMP-7 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The MMP-7 enzyme degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

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