Anti-8-oxo-dG Mouse Monoclonal Antibody [clone: N45.1]

Supplier: Adipogen

JAI-MOG-020P

102981-706EA 373.85 USD

102981-706

Anti-8-oxo-dG Mouse Monoclonal Antibody [clone: N45.1]

Antibodies

8-hydroxy-2'-deoxyguanosine (8-OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals (incl. singlet oxygen and direct photodynamic action) that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer’s disease. 8-OHdG is popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA and can be detected in tissue, serum, urine and other biomaterials.

Type: Primary
Antigen: 8-oxo-dG
Clonality: Monoclonal
Clone: N45.1
Conjugation: Unconjugated
Epitope:
Host: Ascites
Isotype: Mouse IgG1kappa
Reactivity: All, Human

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