Mouse Recombinant Dectin-2 (from HEK293 Cells)
Supplier: 0000027161
AG-40B-0139-C050
102980-270EA
401.54
USD
102980-270
Mouse Recombinant Dectin-2 (from HEK293 Cells)
Proteins and Peptides
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
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