Human Recombinant Jagged-2 (from HEK293 cells)
Supplier: ADIPOGEN CORP MS
AG-40A-0155Y-C010
102980-082EA
304.62
USD
102980-082
Human Recombinant Jagged-2 (from HEK293 cells)
Proteins and Peptides
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
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