Mouse Recombinant CD137L (soluble) (from HEK293 cells)

Supplier: 0000027161

AG-40A-0020Y-C050
102980-034EA 484.62 USD
102980-034
Mouse Recombinant CD137L (soluble) (from HEK293 cells)
Proteins and Peptides

The CD137 ligand (CD137L; 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.

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