Anti-PDPN Monoclonal Antibody [clone: 18H5]

Supplier: Adipogen
AG-20T-0100-C100
102978-596EA 823.85 USD
102978-596
Anti-PDPN Monoclonal Antibody [clone: 18H5]
Antibodies
Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Type: Primary
Antigen: PDPN
Clonality: Monoclonal
Clone: 18H5
Conjugation: Unconjugated
Epitope:
Host:
Isotype: Mouse IgG1
Reactivity: Human
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