Anti-IL-36B Monoclonal Antibody [clone: Jacky-1]

Supplier: Adipogen
AG-20B-0069-C100
102971-628EA 526.15 USD
102971-628
Anti-IL-36B Monoclonal Antibody [clone: Jacky-1]
Antibodies
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Type: Primary
Antigen: IL-36B
Clonality: Monoclonal
Clone: Jacky-1
Conjugation: Unconjugated
Epitope:
Host:
Isotype: Mouse IgG1kappa
Reactivity: Human
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