Anti-FLIP Monoclonal Antibody [clone: NF6]

Supplier: Adipogen
AG-20B-0056-C050 AG-20B-0056-C100
102971-590EA 373.85 USD
102971-590 102971-592
Anti-FLIP Monoclonal Antibody [clone: NF6]
Antibodies
FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

Type: Primary
Antigen: FLIP
Clonality: Monoclonal
Clone: NF6
Conjugation: Unconjugated
Epitope:
Host:
Isotype: Mouse IgG1
Reactivity: Human
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