SMI-4a ≥95% (by NMR)
Supplier: 0000027161
Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth.
Formula:
C₁₁H₆F₃NO₂S Storage Temperature: Freezer |
MDL Number:
MFCD01152003 CAS Number: 327033-36-3 |
Specification Test Results
Purity |
|
Appearance/Color | White to off-white solid. |
Solubility | Soluble in DMSO (at least 5 mg/ml). |
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