Nocodazole ≥98% (by NMR)
Supplier: 0000027161
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Warning
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Microtubule inhibitor. Antitumor compound. Mitosis inhibitor. Arrests the cell cycle at G2/M phase. Promotes tubulin depolymerization. Induces fragmentation of the Golgi complex. Inhibits the T cell antigen receptor. Stimulates the intrinsic GTPase activity of tubulin. Activates the JNK/SAPK signaling pathway. Apoptosis inducer. Autophagy inhibition through prevention of autophagosome-lysosome fusion.
Formula:
C₁₄H₁₁N₃O₃S Storage Temperature: Refrigerator |
MDL Number:
MFCD00005588 CAS Number: 31430-18-9 |
Specification Test Results
Purity |
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Appearance/Color | White to off-white solid. |
Solubility | Soluble in DMSO or dimethylformamide; almost insoluble in water. |
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