Anti-RIG-I Mouse Monoclonal Antibody (Biotin) [clone: Alme-1]

Supplier: Adipogen

AG-20B-0009B-C100

102514-270EA 636.92 USD

102514-270

Anti-RIG-I Mouse Monoclonal Antibody (Biotin) [clone: Alme-1]

Antibodies

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

Stable for at least 1 year after receipt when stored at -20°C.

Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95% (SDS-PAGE)

Type:
Antigen: RIG-I
Clonality: Monoclonal
Clone: Alme-1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse

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