Anti-CD40L Monoclonal Antibody [clone: 24-31]

Supplier: Adipogen
ANC-353-820
102513-024EA 350.31 USD
102513-024
Anti-CD40L Monoclonal Antibody [clone: 24-31]
Antibodies
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and macrophages indicating a possible role for the CD40-CD154 immunoregulatory signaling mechanism during inflammation and immunity in atherogenesis.

  • preservative free

Type: Primary
Antigen: CD40L
Clonality: Monoclonal
Clone: 24-31
Conjugation: Preservative Free
Epitope:
Host:
Isotype: Mouse IgG1
Reactivity: Human, Primate
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