Anti-CD274 Monoclonal Antibody [clone: ANC6H1]

Supplier: Adipogen
ANC-274-820
102512-764EA 350.31 USD
102512-764
Anti-CD274 Monoclonal Antibody [clone: ANC6H1]
Antibodies
CD274 (B7-H1; PD-L1; Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation and is involved in progression of cancer, arthritis and HIV infection. CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in renal cell carcinoma is associated with poor prognosis. Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival.

  • preservative free

Type: Primary
Antigen: CD274
Clonality: Monoclonal
Clone: ANC6H1
Conjugation: Preservative Free
Epitope:
Host:
Isotype: Mouse IgG1kappa
Reactivity: Human
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