Histamine ELISA Plasma/Urine

Supplier: ALPCO DIAGNOSTICS MS

17-HISHU-E01

101720-562EA 783.08 USD

101720-562

Histamine ELISA Plasma/Urine

Assays ELISAs

The histamine ELISA is intended for the quantitative determination of histamine in human plasma and urine.

Contains two ready-to-use controls
Wide standard ranges, convenient measurement of pathological samples without predilution

Histamine belongs to the biogenic amines and is synthesized by decarboxylation from the amino acid histidine. It is synthesized by mast cells, basophils, platelets, histaminergic neurons, and enterochromaffin cells, where it is stored intracellularly in vesicles and released on stimulation. Histamine acts by binding to its four receptors (H1R, H2R, H3R, and H4R) on target cells in various tissues. It causes smooth muscle cell contraction, vasodilation, increased vascular permeability and mucus secretion, tachycardia, alterations of blood pressure, and arrhythmias. Research demonstrates that in humans, histamine is one of the most important mediators and takes part in the initial phase of an anaphylactic reaction ('immediate type' allergy).

Caution: For research use only. Not for use in diagnostic procedures.

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