EPIMARK® Methylated DNA Enrichment Kit, New England Biolabs

Supplier: New England Biolabs (NEB)

EpiMark Methylated DNA Enrichment Kit - 25 rxns

EpiMark Methylated DNA Enrichment Kit - 25 rxns

E2600S

101710-274EA 599 USD

101710-274

EPIMARK® Methylated DNA Enrichment Kit, New England Biolabs

Nucleic Acid Reagents Nucleic Acid Purification Kits and Reagents

The EpiMark Methylated DNA Enrichment Kit enables the enrichment of double-stranded CpG methylated DNA based on CpG methylation density.

It utilizes the methyl-CpG binding domain of human MBD2a protein as a capture agent. The protein is fused to the Fc tail of human IgG1 (MBD2a-Fc), which is coupled to Protein A Magnetic Beads (MBD2a-Fc/Protein A Bead). This stable complex will selectively bind double-stranded methylated CpG containing DNA. The high binding affinity of the MBD2a-Fc coupled beads and optimized reagents increases sensitivity and accuracy. This kit contains all the individual components necessary to achieve enrichment in less than two hours using a four step process.

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