Anti-Insulin Receptor beta Mouse Monoclonal Antibody [clone: C18C4]

Supplier: Enzo Life Sciences
905-683-100
101410-452EA 418.56 USD
101410-452
Anti-Insulin Receptor beta Mouse Monoclonal Antibody [clone: C18C4]
Antibodies
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Type: Primary
Antigen: Insulin Receptor beta
Clonality: Monoclonal
Clone: C18C4
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat, Sheep, Pig, Bovine, Hamster, Rabbit
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