Anti-THOC7 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-THOC7 Rabbit Polyclonal Antibody

Anti-THOC7 Rabbit Polyclonal Antibody

Anti-THOC7 Rabbit Polyclonal Antibody

Anti-THOC7 Rabbit Polyclonal Antibody

Anti-THOC7 Rabbit Polyclonal Antibody

Anti-THOC7 Rabbit Polyclonal Antibody

17881-1-AP-150UL

10095-950EA 462.47 USD

10095-950

Anti-THOC7 Rabbit Polyclonal Antibody

Antibodies

THOC7 is a member of the THO complex that associate with the mRNA export apparatus. It is required for efficient export of polyadenylated RNA. It acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

Western Blot: Mouse Testis Tissue, 1:1000-1:10000; IHC: Human Kidney Tissue, 1:20-1:200

Type: Primary
Antigen: THOC7
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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