Anti-SCARA5 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-SCARA5 Rabbit Polyclonal Antibody

Anti-SCARA5 Rabbit Polyclonal Antibody

55390-1-AP-150UL

10094-168EA 462.47 USD

10094-168

Anti-SCARA5 Rabbit Polyclonal Antibody

Antibodies

SCARA5 belongs to the SCARA5 family. It is a ferritin receptor that mediates non-transferrin-dependent delivery of iron. SCARA5 mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. SCARA5 binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). This antibody can recognize isoform 1,2 and 3 of SCARA5.

Western Blot: Mouse Liver Tissue, 1:200-1:1000

Type: Primary
Antigen: SCARA5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse

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